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当前和未来的方向

 

Foreword
 
We are pleased to present this update to the educational slide kit Insulin Therapy in Type2 Diabetes: Current and Future Directions. As the incidence of type 2 diabetes continuesto increase into the new millennium, so too does our knowledge of the disease and themethods with which we may successfully manage it. Based on data presented at the 59thScientific Session of the American Diabetes Association and the other recent studies, thisupdate includes some of the latest information on the treatment of type 2 diabetes.
 
New data are presented from studies of both clinical and economic trends in diabetes care,diabetes treatment in the primary care setting, the pediatric population, and management ofgestational diabetes. Also included are findings from clinical trials of the new thiazolidinediones,pioglitazone and rosiglitazone; new insulin analogues such as insulin aspart andinsulin glargine; and novel methods of insulin delivery such as oral inhalation.
 
We hope you will find these slides useful in preparing comprehensive, up-to-date presentationsor lectures on the management of type 2 diabetes. Thank you for your efforts in presentingthis educational material.
 
Table of Contents
 
2 SLIDE 1. Attaining Glycemic Goals for Type 2 Diabetes Using
 
Monotherapy
 
2 SLIDE 2. Attaining Glycemic Goals Using Monotherapy in Obese Patients
 
With Type 2 Diabetes
 
3 SLIDE 3. Diabetes Management in Primary Care
 
4 SLIDE 4. Intrasubject Variability: NPH Insulin
 
4 SLIDE 5. Intrasubject Variability: Ultralente Insulin
 
5 SLIDE 6. Intrasubject Variability: Insulin Glargine
 
5 SLIDE 7. Insulin Glargine vs NPH Insulin: Glycemic Control and
 
Hypoglycemia
 
6 SLIDE 8. Pharmacodynamics/Pharmacokinetics of Insulin Aspart vs
 
Regular Insulin
 
6 SLIDE 9. Pharmacodynamics/Pharmacokinetics of NN304 vs
 
NPH Insulin
 
7 SLIDE 10. New Concepts in Insulin Delivery: Changes in Plasma Glucose
 
With Inhaled Human Insulin
 
7 SLIDE 11. Effects of Pioglitazone, Rosiglitazone, and Troglitazone on Liver
 
Function
 
7 SLIDE 12. Efficacy and Safety of Triple Therapy: Troglitazone + Metformin +
 
Sulfonylurea
 
8 SLIDE 13. Improved Glycemic Control With Rosiglitazone in Patients With
 
Type 2 Diabetes
 
9 SLIDE 14. Effects of Pioglitazone on Glycemia in Patients With Type 2
 
Diabetes
 
10 SLIDE 15. Management of Gestational Diabetes Mellitus
 
11 SLIDE 16. Type 2 Diabetes in the Pediatric Population: First Nation Data
 
11 SLIDE 17. Clinical Trends in Practice Outcomes of Diabetes Care
 
12 SLIDE 18. Economic Trends in Type 2 Diabetes Care
 
 
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